links to the PubMed entry

Argyris, J., Dahal, P., Truco, M.-J., Ochoa, O., David W. Still, D.W., Michelmore, R.W., & Bradford, K.J. (2007). Genetic analysis of lettuce seed thermoinhibition. Acta Hort.

Tan, X., Meyers, B.C., Kozik, A., Morgante, M., West, M., St Clair, D., Bent, A., & Michelmore, R.W. (2007). Global Expression Analysis of NBS-LRR Encoding Genes in Arabidopsis. BMC Plant Biology.

Chen, J., Agrawal, V., Rattray, M., West, M.A.L., St.Clair, D.A., Michelmore, R.W., Coughlan, S.J., Meyers, B.C. (2007). A comparison of microarray and MPSS technology platforms for expression analysis of Arabidopsis. BMC Genomics 8:414.

Truco, M.J., Antonise, R., Lavelle, D., Ochoa, O., Kozik, A, Witsenboer, H., Fort, S., Jeuken, M.J.W., Kesseli, R. V., Lindhout, P., Michelmore, R.W., Peleman, J. (2007). A high-density, integrated genetic linkage map of lettuce (Lactuca spp.). Theor. Appl. Genet. 115:735-746.

Wroblewski, T., Piskurewicz, U., Tomczak, A., Ochoa, O., & Michelmore, R.W. (2007). Silencing of the major family of NBS-LRR-encoding genes in lettuce results in the loss of multiple resistance specificities. Plant J.  51:803-818.

Zhang, F.Z, Wagstaff, C., Rae, A.M., Kaur, A., Keevil, W.C., Rothwell, S.D., Clarkson, G.J.J., Michelmore, R.W., Truco, M.J., Dixon, M.S., Taylor, G. (2007). QTL for shelf life in lettuce co-locate with those for leaf biophysical properties but not for leaf developmental traits. J. Exp. Bot. 58: 1433-1449.

van Leeuwen, H., Kliebenstein, D.J., West, M.A.L., Kim, K., van Poecke, R., Katagiri, F., Michelmore, R.W., Doerge, R.W., St.Clair, D.A. (2007). Natural variation among Arabidopsis thaliana accessions for transcriptome response to exogenous salicylic acid. Plant Cell 19:2099-110.

Church, S.A., Livingstone, K., Lai, Z., Kozik, A., Knapp, S.J., Michelmore, R.W., Rieseberg, L.H. (2007). Using variable rate models to identify genes under selection in pairwise comparisons: its validity and limitations for EST sequences. J. Mol. Evol. 64:171-180.

West, M.A.L., Kim, K., Kliebenstein, D., van Leeuwen, H., Michelmore, R.W., Doerge, R.W., St Clair, D.A. (2007). Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis. Genetics 175:1441-50.

Rose, L.E., Michelmore, R.W. & Langley, C.H. (2007). Natural variation in the Pto disease resistance gene within species of wild tomato (Lycopersicon) II. Population genetics of Pto. Genetics 175:1307-1319.

Timms, L., Jimenez, R., Chase, M., Lavelle, D., McHale, L., Kozik, A., Lai, Z., Heesacker, A., Knapp, S., Rieseberg, L., Michelmore, R., Kesseli, R. (2006). Analyses of synteny between Arabidopsis thaliana and species in the Asteraceae reveal a complex network of small syntenic segments and major chromosomal rearrangements. Genetics 173:2227-35.

Bushman, B.S., Scholte, A.A., Cornish, K., Scott, D.J., Brichta, J.L., Vederas, J.C., Ochoa, O., Michelmore, R.W., Shintani, D., Knapp, S.J. (2006). Identification and characterization of natural rubber from two Lactuca species. Phytochemistry 67:2590-2596.

Kuang, H., Ochoa, O.E., Nevo, E., Michelmore, R.W. (2006). The disease resistance gene Dm3 is infrequent in natural populations of Lactuca serriola due to deletions and frequent gene conversions. Plant J. 47(1):38-48. Also available on line.

West, M. A.L., van Leeuwen, H., Kozik, A., Kliebenstein, D. J., Doerge, R. W., St.Clair, D. A., Michelmore, R.W. (2006). High-density haplotyping with microarray-based expression and single feature polymorphism markers in Arabidopsis. Genome Research 16: 702-712.

McHale, L., Tan, X., Koehl, P., Michelmore, R.W. (2006). Plant NBS-LRR proteins: adaptable guards. Genome Biology 7:212.

Kliebenstein D.J., West M.A., van Leeuwen H., Kim K., Doerge R.W., Michelmore R.W., St Clair D.A. (2006). Genomic survey of gene expression diversity in Arabidopsis thaliana. Genetics 172:1179-1189.

Argyris J., Truco M.J., Ochoa O., Knapp S.J., Still D.W., Lenssen G.M., Schut J.W., Michelmore R.W., Bradford K.J. (2005). Quantitative trait loci associated with seed and seedling traits in Lactuca. Theor. Appl. Genet. 111:1365-1376.

Rose, L., Langley, C., Bernal, A., Michelmore, R. (2005). Natural variation in the Pto pathogen resistance gene within species of wild tomato (Lycopersicon): I. Functional analysis of Pto alleles. Genetics 171:345-57.

Bernal, A., Pan, Q., Pollack, J., Rose, L., Willets, N., Kozik, A., Michelmore, R. (2005). Functional dissection of the Pto resistance gene using DNA shuffling. J. Biol. Chem. 280:23073-83.

Kim, K., West, M.A.L., Michelmore, R.W., St. Clair, D.A., and Doerge, R.W. (2005). Old methods for new ideas: genetic dissection of the determinants of gene expression levels. In: Genome Exploitation: Data Mining the Genome. J.P. Gustafson, R. Shoemaker, J.W. Snape, eds. 23rd Stadler Symposium. Springer Science pp 87 - 107.

Wroblewski, T., Tomczak, A., and Michelmore, R. W. (2005). Optimization of Agrobacterium-mediated transient assays of gene expression in lettuce, tomato and Arabidopsis. Plant Biotechnology Journal 3: 259-273.

Kuang, H., Woo, S.-S., Meyers, B., Nevo, E. and Michelmore, R.W. (2004). Multiple genetic processes result in heterogeneous rates of evolution within the major cluster of disease resistance genes in lettuce. Plant Cell 16: 2870-2894.

Rose L.E., Bittner-Eddy, P.D., Langley, C.H., Holub, E.B., Michelmore, R.W., and Beynon, J.L. (2004). The maintenance of extreme amino acid diversity at the resistance gene RPP13 in Arabidopsis thaliana. Genetics 166: 1517-1527.

Brown, S., Koike, S., Ochoa, O., Laemmlen, F. and Michelmore, R.W. (2004). Insensitivity to the fungicide, fosetyl-aluminum, in California isolates of lettuce downy mildew, Bremia lactucae. Plant Disease 46: 1059-1069.

Cannon S.B., Kozik A., Chan B., Michelmore R., Young N.D. (2003). DiagHunter and GenoPix2D: programs for genomic comparisons, large-scale homology-discovery, and visualization. Genome Biology 4:R68.

Moreno-Vaquez, S., Ochoa, O., Faber, N., Chao, S., Jacobs, J.M.E., Maisonneuve, B., Kesseli, R., Michelmore, R.W. (2003). SNP-based codominant markers for a recessive gene conferring resistance to corky root rot (Rhizomonas suberifaciens) in lettuce (Lactucae sativa). Genome 46:1059-1069.

Michelmore, R.W. (2003). Impact zone: genomics and breeding for durable disease resistance. Current Opinion in Plant Biology 6:397-404.

Sicard, D., Legg, E.J., Brown, S., Babu, N., Ochoa, O., Michelmore, R.W. (2003). A genetic map of the lettuce downy mildew fungus, Bremia lactucae constructed from molecular markers and avirulence genes. Fungal Genetics and Biology 39:16-30.

Meyers, B.C., Kozik, A., Griego, A., Kuang, H. and Michelmore, R.W. (2003). Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis. Plant Cell 15:809-834.

Saltveit M.E., Ochoa, O., Reinaldo Campos-Vargas, R., and Richard Michelmore, R.W. (2003). Lines of lettuce selected for ethylene insensitivity at the seedling stage displayed variable responses to ethylene or wounding in mature heads. Postharvest Biology and Technology 27: 277-283.

Meyers, B.C., Morgante, M, and Michelmore, R.W. (2002). TIR-X and TIT-NBS proteins: two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant species. Plant Journal 32:77-92.

Mondragón-Palomino, M., Meyers, B.C., Michelmore, R.W., Gaut, B.S. (2002). Patterns of Positive Selection in the Complete NBS-LRR Gene Family of Arabidopsis thaliana. Genome Res. 12: 1305-1315.

Kozik, A., Michelmore, R.W., Knapp, S.J., Matvienko, M., S., Rieseberg, L., Lin, H., van Damme, M., Lavelle, D., Chevalier, P., Ziegle, J., Ellison, P. Kolkman, J., Slabaugh, M.S., Livingston, K., Zhou, Lai, Z., Church, S., Edberg, S., Jackson, L., Bradford, K., et al. (2002). Lettuce and Sunflower ESTs from the Compositae Genome Project.

Michelmore, R.W. (2002). Natural and artificial evolution of disease resistance genes. Proc. 10^th Int. Congr. Mol. Plant Microbe Interact. pp 23 – 29.

Kozik, A., Kochetkova, E., Michelmore, R.W. (2002). GenomePixelizer – a visualization program for comparative genomics within and between species. Bioinformatics 18:335-336.

Chang, J.H., Tai, Y.-S., Bernal, A.J., Lavelle, D.T., Staskawicz, B.J., Michelmore, R.W. (2002). Functional analysis of the Pto resistance gene family in tomato. Mol. Plant Microbe Interact. 15:281-191.

Shen, K.A., Chin, D.B., Arroyo-Garcia, R., Ochoa, O.E., Lavelle, D.O., Wroblewski, T., Meyers B.C., and Michelmore, R.W. (2002). Dm3 is one member of a large constitutively-expressed family of NBS-LRR encoding genes. Mol. Plant Microbe Interact. 15:251-261.

Gedil, M.A., Slabaugh, M.B., Berry, S., Johnson, R., Michelmore, R.W., Miller, J., Gulya, T., Knapp, S.J. (2001). Candidate disease resistance genes in sunflower cloned using conserved nucleotide binding site motifs: genetic mapping and linkage to the Pi1 gene for resistance to downy mildew. Genome 44:205-212.

Chang, J.H., Tobias, C.M., Staskawicz, B.J., Michelmore, R.W. (2001). Functional studies of the bacterial avirulence protein AvrPto by mutational analysis. Mol. Plant Microbe Interact. 14:451-459.

Chin, D.B., Arroyo-Garcia, R., Ochoa, O., Kesseli, R.V., Lavelle, D.O., Michelmore, R.W. (2001). Recombination and spontaneous mutation at the major cluster of resistance genes in lettuce (Lactuca sativa). Genetics 157:831-849.

Johnson, W.C., Jackson, L.E. Ochoa, O., van Wijk, R., Peleman, J., St.Clair, D.A., Michelmore, R.W. (2000). A shallow-rooted crop and its wild progenitor differ at loci determining root architecture and deep soil water extraction. Theor. Appl. Genet. 101:1066-1073.

Chang, J.H., Rathjen, J.P. Bernal, A.J., Staskawicz, B.J., Michelmore, R.W. (2000). AvrPto enhances growth and necrosis caused by Pseudomonas syringae pv. tomato in tomato lines lacking functional Pto or Prf genes. Mol. Plant Microbe Interact. 13: 568-571.

Michelmore, R.W. (2000). Genomic approaches to plant disease resistance. Curr. Opin. Plant Biol. 3:125-131.

Michelmore R.W. (1999). Structure, function and evolution of resistance gene clusters in plants, particularly the Pto and Dm3 loci. Proc. 9^th Int. Congr. Mol. Plant Microbe Interact. pp 232-237.

Irwin S.V., Kesseli R.V., Waycott W., Ryder E.J. Cho J.J., and Michelmore R.W. (1999). Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross of lettuce. Genome 42:982-986.

Meyers, B.C., Dickerman, A.W., Michelmore, R.W., Sivaramakrishnan, S., Sobral, B.W. and Young, N.D. (1999). Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily. Plant J. 20:317-332.

Sicard, D., Woo, S.-S., Arroyo-Garcia, R., Ochoa. O., Nguyen, D., Korol, A., Nevo, E., and Michelmore, R.W. (1999). Molecular diversity at the major cluster of disease resistance genes in cultivated and wild Lactuca spp. Theor. Appl. Genet., 99:405-418.

Rathjen, J.P., Chang, J.H., Staskawicz, B.S., Michelmore, R.W. (1999). Activated Pto mediates the AvrPto-dependent hypersensitive disease resistance response in N. benthamiana and tomato. EMBO J 18:3232-3240.

Waycott, W., Fort, S., Ryder, E.J., Michelmore, R.W. (1999). Mapping of twelve morphological genes relative to molecular markers in lettuce (Lactuca sativa L.). Heredity 82:245-251.

Shiue, Y.-L., Bickel, L.A., Caetano, A.R., Millon, L.V., Clark, R., Eggleston, M.L., Michelmore, R.W., Bailey, E., Guerin, G., Godard, S., Mickelson, J.R., Valberg, S.J., Murray, J.D., Bowling, A.T. (1999). A syntenic map of the horse genome comprised of 240 microsatellite and RAPD markers. Animal Genetics 30:1-9.

Michelmore, R.W. and Meyers, B.C. (1998). Clusters of resistance genes in plants evolve by divergent selection and a birth-and-death process. Genome Research 8:1113-1130. (http://www.genome.org/)

Meyers, B.C., Shen, K.A., Rohani, P., Gaut, B.S., Michelmore, R.W. (1998). Receptor-like genes in the major resistance locus of lettuce are subject to divergent selection. Plant Cell 10:1833-1846. (http://www.plantcell.org/)

Meyers, B.C., Chin, D.B., Shen, K.A., Sivaramakrishnan, S., Lavelle, D.O., Zhang, Z., Michelmore, R.W. (1998). The major resistance gene cluster in lettuce is highly duplicated and spans several megabases. Plant Cell 10:1817-1832. (http://www.plantcell.org/)

Shen, K.A., Meyers, B.C., Islam-Faridi, M.N. Chin, D.B., Stelly, D.M., Michelmore, R.W. (1998). Resistance gene candidates identified using PCR with degenerate primers map to resistance genes clusters in lettuce. Mol. Plant-Microbe Interact.. 11:815-823.

Witsenboer, H., Vogel, J., Michelmore, R.W. (1998). Identification, genetic localization and allelic diversity of selectively amplified microsatellite polymorphic loci (SAMPL) in lettuce and wild relatives (Lactuca spp.). Genome 40:923-936.

Okubara, P.A., Arroyo-Garcia, R., Shen, K.A., Mazier, M. Meyers, B.C., Ochoa, O., Kim, Shinje, S., Yang, C.-H., Michelmore, R.W. (1997). A transgenic mutant of Lactuca sativa (lettuce) with a T-DNA tightly linked to the loss of downy mildew resistance. Molec. Plant Microbe Interact. 10:970-977.

Fritjers, A.C.J., Zhang, Z., van Damme, M., Wang, G.-L., Ronald, P.C. and Michelmore, R.W. (1997). Construction of a bacterial artificial chromosome library containing large EcoRI and HindIII genomic fragments of lettuce. Theor. Appl. Genet. 94:390-399.

Kesseli, R. V. and Michelmore, R. W. (1997). The Compositae: systematically fascinating but specifically neglected. In: Genome Mapping in Plants, A.H. Paterson ed. R.G. Landes Co. Georgetown, TX. pp179 - 191.

Kesseli, R., H. Witsenboer, M. Hill, Y.-H. Zhang, M. Chase and R. Michelmore. (1996). Genome organization and evolution of disease resistance genes in Lactuca spp. and the prospects for comparative mapping in the compositae. In Proc. Int. Compositae Conf., Kew, 1994. Vol. 2. Biology and Utilization. Eds. P. Caligari & D.J.N. Hind. Royal Botanic Gardens, Kew. pp 1-8.

Hill, M., Witsenboer, H., Zabeau, M., Vos, P., Kesseli, R., Michelmore, R. W. (1996). AFLP fingerprinting as a tool for studying genetic relationships in Lactuca spp. Theor. Appl. Genet. 93:1202-1210.

Scofield, S.R. Tobias, C.M., Rathjen, J.P., Chang, J.H., Lavelle, D.T., Michelmore, R.W., and Staskawicz, B.J. (1996). Molecular basis of gene-for-gene specificity in bacterial speck disease of tomato. Science 274:2063-2065.

Michelmore, R.W. (1996). Flood warning: resistance genes unleashed. (News and Views) Nature Genetics 14:376-378.

Michelmore, R.W. (1996). Big news for plant transformation. (Commentary) Nature Biotechnology 14:1653-1654.

Anderson, P. A., Okubara, P.A., Arroyo-Garcia, R., Meyers, B.C., Michelmore, R.W. (1996). Molecular analysis of irradiation-induced and spontaneous deletion mutants at a disease resistance locus in Lactuca sativa. Mol. Gen. Genet. 251:316-325.

Michelmore, R. (1995). Molecular approaches to manipulation of disease resistance genes. Annu. Rev. Phytopathol. 15:393-427.

Witsenboer, H., Kesseli, R.V., Fortin, M., Stangellini, M., Michelmore, R.W. (1995). Sources and genetic structure of a cluster of genes for resistance to three pathogens in lettuce. Theor. Appl. Genet. 91:178-188.

Michelmore, R.W. (1995). Isolation of disease resistance genes from crop plants. Curr. Opinions in Biotechnology 6:145-152.

Robbins, M.A., Witsenboer, H., Michelmore, R.W. Laliberte, J.-F., and Fortin M.G. (1994). Genetic mapping of turnip mosaic virus resistance in Lactuca sativa. Theor. Appl. Genet. 89:583-589.

Maisoneuve, B., Anderson, P. and Michelmore, R.W. (1994). Rapid mapping of two genes for resistance to downy mildew derived from Lactuca serriola to existing clusters of resistance genes. Theor. Appl. Genet. 89:96-104.

Michelmore, R.W., Kesseli, R.V., and Ryder, E.J. (1994). Genetic mapping in lettuce. In: DNA Markers in Plants, eds, R.L. Phillips and I.K. Vasil. Kluwer Acad. Pub. pp 223-239.

Michelmore, R.W., Anderson, P., Okubara, P., Witsenboer, H. (1994). Clusters of resistance genes in lettuce: map-based cloning in non-intensively studied species. NATO ASI series, Vol. H 81, Pl. Mol. Biol. Eds. G. Coruzzi & P. Puigdomenech. Springer-Verlag, Berlin. pp 501-509.

Okubara, P., P. Anderson, R. W., Ochoa, O., Michelmore (1994). Mutation analysis of genes for resistance to downy mildew in lettuce. Genetics 137:867-874.

Kesseli, R.V., I. Paran, and R.W. Michelmore (1994). Analysis of a detailed genetic linkage map of Lactuca sativa (lettuce) constructed from RFLP and RAPD markers. Genetics 136:1435-1446.

Judelson, H.S., Dudler, R., Pieterse, C.M.J., Unkles, S.E. and Michelmore, R.W. (1993). Expression and antisense inhibition of transgenes in Phytophthora infestans is modulated by choice of promoter and position effects. Gene 133:63-69.

Kesseli, R.V., Witsenboer, H., Vandemark, G.J., Stangellini, M.E., and Michelmore, R.W. (1993). Recessive resistance to Plasmopara lactucae-radicis maps by bulked segregant analysis to a cluster of dominant resistance genes in lettuce. Mol. Pl. Microbe Interact. 6:722-728.

Francis, D.M. and R.W. Michelmore (1993). Two classes of chromosome-sized molecules are present in Bremia lactucae. Exptal. Mycol. 17:284-300.

Yang, C.-H., Scofield, S., Caroll, B., Jones, J., Michelmore, R.W. (1993). Transposition of Ds in plants of lettuce. Mol. Gen. Genet. 241:389-398.

Yang, C.-H., J. Ellis, and R.W. Michelmore. (1993). Infrequent transposition of Ac in lettuce. Pl. Mol. Biol. 22:973-805.

Kesseli, R.V., Paran, I., Ochoa, O., Wang, W.-C., and Michelmore, R.W. (1993). Linkage map of lettuce (Lactuca sativa). In: Genetic Maps, 6th Ed. S. J. O'Brien (ed.). Cold Spring Harbor Press. 6.229-233.

Paran, I. and R.W. Michelmore (1993). Development of reliable PCR-based markers linked to downy mildew resistance genes in lettuce. Theor. Appl. Genet. 85:985-993.

Michelmore, R.W., Anderson, P.A., Witsenboer, H., Kesseli, R.V., Paran, I., Francis, D.M. and Ochoa, O. (1993). Molecular markers and genome analysis in the manipulation of lettuce downy mildew. In: Advances in Molecular Genetics of Plant Microbe Interactions, eds E. Nester & D.-P. Verma, 2:517-523.

Judelson, H.S. and R.W. Michelmore (1992). Temperature and genotype interactions in the expression of host resistance in lettuce downy mildew. Physiol. Mol. Plant Pathol. 40:233-245.

Michelmore, R.W., R.V. Kesseli, D.M. Francis, I. Paran, M.G. Fortin, and C.-H. Yang (1992). Strategies for cloning plant disease resistance genes. In: Molecular Plant Pathology - A Practical Approach. Ed. S. Gurr, M.J. McPherson and D.J. Bowles. IRL Press, Oxford. Vol. 2, pp233-288.

Paran, I., R.V. Kesseli, and R.W. Michelmore (1992). Recent amplification of triose phosphate isomerase related sequences in lettuce. Genome 35:627-635.

Judelson, H.S., B.M. Tyler, and R.W. Michelmore (1992). Regulatory sequences for expressing genes in oomycete fungi. Mol. Gen. Genet. 234:138-146.

Vandemark, G.J., M.E. Stangellini, S.L. Rasmussen, and R.W. Michelmore (1991). Inheritance of resistance in lettuce to Plasmopara lactucae-radicis. Phytopathology 82:272-274.

Paran, I., R.V. Kesseli, and R.W. Michelmore (1991). Identification of RFLP and RAPD markers linked to downy mildew resistance genes in lettuce using near-isogenic lines. Genome 34:1021-1027.

Judelson, H.S., B. Tyler, and R.W. Michelmore (1991). Stable transformation of the potato late blight fungus, Phytophthora infestans. Mol. Plant-Microbe Interact. 4:602-607.

Michelmore, R.W., I. Paran, and R.V. Kesseli (1991). Identification of markers linked to disease resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions using segregating populations. Proc. Natl. Acad. Sci. 88:9828-9832.